The FDA says manufacturers haven't proven the ingredients are safe for long-term daily use or more effective than just plain old soap and water.
The FDA previously asked for data from manufacturers to support claims the ingredients, most notably triclosan and triclocarban, were safe and effective. The agency has now concluded those claims equate to misbranding.
Some studies have suggested that triclosan can disrupt hormones in animals, but its effects on humans are still unclear.
The American Cleaning Institute defended the safety and efficacy of antibacterial soaps, saying manufacturers will keep working to provide more data on antibacterial ingredients.
Manufacturers have a year to remove the ingredients from their products, but the FDA's ruling doesn't affect hand sanitizers or "antibacterial products used in health care settings."